INDICATIONS: MartiDerm blisters proteoglycan is indicated for the treatment of face and neck wrinkles, flaking processes, dry skin, sagging and all manifestations of cutaneous fotoenvelecimiento. Your daytime use allows associating with other specific treatments antiaging (retinoic acid, alpha-hydroxy acids, selenomethionine, etc..). PROPERTIES: The formula MartiDerm blisters proteoglycan is studied to improve and reduce skin aging caused by the passage of time and sun exposure, restoring skin in a short space of time, the normal degree of hydration, smoothness, flexibility and firmness. INSTRUCTIONS: - Clean and degrease the skin. - Shake the vial before application. - Apply daily, the contents of a blister on the face and neck by gently massaging the pads of fingers coughing, insisting in the most affected areas until its complete absorption. - If the contents of an ampoule is excessive, it can be used for hydration of other body parts (hands, arms, neck, etc..). - After 10 'of the application, you can withdraw excess fluid that has not been absorbed with cotton remover and apply a day cream or makeup routine. EFFECTS OF VIALS: IMMEDIATE: immediate action as may apply when you want to give an appearance of smoothness and luminosity. ALONG TERM: Gradual elimination of wrinkles, partially reversing structural damage and slowing the skin aging process. This effect is especially noticeable at the level of appearance and mechanical properties of the skin: Reaffirm and hydrate. Ascorbic acid or vitamin C (C6H608) is a querolactona structurally similar to glucose, with various physiological functions. 1 - acts as cofactor of multiple enzymes involved in the synthesis of collagen, carnitine, catecholamines, oxytocin, and in the microsomal metabolism of some drugs and folic acid. 2 - develops a protective role on the p-phenyl-pyruvic oxidase involved in the metabolism of tyrosine. 3 - stimulates the synthesis of collagen, proteoglycans and other organic constituents of the intercellular matrix. 4 - Has antioxidant and free radical neutralizing capacity. Although many therapeutic potential attributed to vitamin C, the clearest indication today is the prevention of skin photoaging. Vitamin F essential fatty acids contributes to regulate the state of hydration. The propylene glycol content promotes penetration of the active components of the blisters. ACTING AS THE PROTEOGLYCAN: Chronic exposure to UV radiation produces obvious changes in the elastic and collagen fibers and increases the formationof GAGs accumulation nonfunctional present in the dermis. Among the activities carried proteoglycans in connective tissue include the following: 1) Increase the cell metabolism and proliferation. 2) Increase the "turn over" of fatty acids. 3) Anti-inflammatory action. 4) accelerate the healing process. 5) Increase the connection of cells with the extracellular components of their environment. 6) Increase communication between cells. 7) have a structural role in connective tissue. 8) Regulate the water content of the tissue and water retention capacity. All this results thus in an increase of the mechanical resistance of the skin against shock and friction also represent a barrier against the diffusion of certain bacteria that can invade the tissues. Moreover, given the capacity of these polysugars to retain water, it absorbs a volume of up to 1,000 times higher than PG, contributing to skin turgor and nutrition.