Actions and mechanisms: -- [Nervous stimulant]. In experimental animals has shown that ginseng increases the time of resistance to fatigue, increases thermogenesis improve tolerance to cold and stimulates the production of ribosomes liver. However these figures have not been tested in humans. -- [Hypoglycaemic]. The ginseng increases insulin secretion and also regulates the formation of liver glycogen. In in vitro tests on rat islets of Langerhans revealed that ginseng increases the release of insulin. In tests in vivo in rats showed an increase in the number of insulin receptors in the spinal cord and a reduction in glucocorticoid receptors in rat brains. In a randomised, double-blind, placebo-controlled, it was found the hypoglycaemic effect of ginseng. We chose 36 patients (20 women and 16 men) and settled 3 groups receiving 0, 100 and 200 mg ginseng/24 hours. It was found that at doses of 200 mg/24 hours, ginseng decreased fasting blood glucose and glycosylated hemoglobin concentration. -- [Hipolipemiante]. The ginseng stimulates the-lipoprotein lipase, an enzyme that reduces levels of chylomicrons and VLDL blood and therefore cholesterol and triglycerides. Indicators: -- [Fatigue], [fatigue] or [MENTAL exhaustion]. POSOLOGIA: 1 capsule or comprimido/8-12 hours. The capsules and tablets should be taken by mouth with a glass of water. The duration of treatment should not exceed 3 months. Caution: -- [Cardiac arrhythmia], [hypertension]. Ginseng has a cardiovascular stimulant effects, which could lead to hypertensive crisis and cardiac arrhythmias. -- [Diabetes]. The ginseng could lead to a decrease in blood glucose, which could enhance the effects of antidiabetic drugs. In case of diabetic patients, with treatment set up and adjusted, it is recommended again monitor glucose levels at the beginning and end of treatment with ginseng. Special warnings: Council to patients: -- This medicine must not be used by pregnant women. -- Is not recommended for use of ginseng for an extended period of 3 months or more doses greater than 1 g / day, because it can cause disorders similar to those produced by steroids (high blood pressure, nervousness, insomnia). They can also observed estrogenic effects (gynecological disorders). Interaction: -- Anticoagulants like warfarin, heparin or antiplatelet. The ginseng could enhance the effects of antiplatelet, or oral anticoagulants heparin, favoring the emergence of bleeding. We must avoid the association. -- Antidiabetic. The ginseng could enhance the effects of insulin or the sulfonylureas and potentially a hypoglycemia. For administration of this drug along with insulin or sulfonylureas, shall be adjusted doses of the same. -- Digital. The ginseng could enhance the therapeutic effects and toxicity of digitalis to increase their levels in blood. Caution should be exercised and monitored concentrations of digoxin. -- Estrogens, steroids. The ginseng could enhance the effects and toxicity of steroids and estrogen agonists. -- Inhibitors of monoamino-oxidase (IMA). The ginseng could enhance the effects of inhibitors of monoamino-oxidase (IMA) may cause hypertensive crisis, headaches, tremors and hobbies. USE under special conditions: The ginseng could induce spontaneous abortions because of their potential effects estrogen. In addition, cases have been reported of hypospadias and facial deformities in fetuses of pregnant women consuming ginseng, although it has not been demonstrated. There has been no clinical trials in humans, so the use of ginseng is accepted only if no safer alternative therapies. USE under special conditions: It is not known whether the components of ginseng are excreted in significant quantities in breast milk, and whether it might interfere with the child. It is recommended suspending breastfeeding or prevent the administration of this medicine.